Contents
EXECUTIVE SUMMARY
1. TISSUE ENGINEERING AND REGENERATIVE MEDICINE TECHNOLOGIES
1.1 Biomaterials Technologies
1.1.1 Synthetic Materials
1.1.2 Biologically Derived Materials
1.1.3 Genetically Engineered Materials
1.2 Stem Cell Technologies
1.2.1 Stem Cell Sources
1.2.2 Stem Cell Extraction Techniques
1.2.3 Stem Cell Expansion
1.2.4 Stem Cell Delivery
1.2.5 Existing and Development-Stage Stem Cell Products
1.3 Cell Culture Technologies
1.4 Immunopassivation and Immunomodulation
1.4.1 Chimeric Immunopassivation
1.4.2 Immunomodulation
1.4.3 Cell Encapsulation
2. CARDIOVASCULAR APPLICATIONS OF TISSUE ENGINEERING AND REGENERATIVE MEDICINE
2.1 Cardiovascular Disease Incidence and Prevalence
2.2 Cardiovascular Applications and Market Potential
2.2.1 Heart Valve Repair and Replacement
2.2.2 Heart Failure and Myocardial Tissue Regeneration
2.2.3 Applications in Peripheral Vascular Disease
2.2.4 Applications in Coronary Artery Disease
2.3 Market Forecast for Cardiovascular Applications
2.4 Cardiovascular Market Drivers and Limiters
2.5 Leading Companies in Cardiovascular Tissue Engineering and Regenerative Medicine
CHAPTER 3: ORTHOPAEDIC APPLICATIONS AND MARKETS
3.1 Orthopaedic Disease Incidence and Existing Therapies
3.1.1 Bone Fractures/Bone Repair and Replacement
3.1.2 Cartilage Degeneration and Repair
3.1.2.1 Osteochondral Allografts
3.1.2.2 Osteochondral Autograft Transfer System and Mosaicplasty
3.1.2.3 Autologous Chondrocyte Transplantation
3.1.2.4 Matrix-induced Autologous Chondrocyte Implantation
3.1.2.5 High Tibial Osteotomy
3.1.3 Meniscus Defects and Repair
3.1.4 Ligament and Tendon Injuries and Repair
3.1.5 Joint Degeneration and Destruction
3.1.6 Spinal Disc Degeneration and Repair
3.2 Emerging Tissue Engineering and Regenerative Medicine Technologies for Orthopaedic Applications and Markets
3.2.1 Bone Repair and Replacement
3.2.2 Cartilage Repair and Replacement
3.2.2.1 Cartilage Autograft Implantation System
3.2.2.2 Other Emerging Cartilage Repair and Replacement Technologies
3.2.3 Meniscus Repair and Replacement
3.2.4 Tendon and Ligament Repair and Replacement
3.2.5 Spinal Disc Repair and Replacement
3.2.6 Market Size, Market Potential and Forecast for Orthopaedic Applications
3.3 Market Drivers and Limiters
3.4 Leading Companies in Orthopaedic Tissue Engineering
CHAPTER 4: APPLICATIONS AND MARKETS IN NEUROLOGY
4.1 Neurological Disease Prevalence and Incidence
4.2 Tissue Engineering and Regenerative Medicine Technologies for Neurological Applications and Market Potential
4.2.1 Tissue Engineering and Regenerative Medicine for Spinal Cord Injury and Amytrophic Lateral Sclerosis
4.2.2 Cell Implants for Parkinson’s Disease
4.2.3 Cell Transplants for Epilepsy Treatment
4.2.4 Stem Cell Therapy for Multiple Sclerosis
4.2.5 Cell Therapy for Peripheral Nerve Injury
4.2.6 Tissue Engineering Therapies for Stroke
4.2.7 Tissue Engineering Therapies for Alzheimer’s Disease
4.2.8 Tissue Engineering and Cell Transplant Therapies for Central Nervous System Disorders
4.3 Market Forecast for Neurological Applications
4.4 Market Drivers and Limiters
4.5 Leading Companies in Neurological Tissue Engineering
CHAPTER 5: APPLICATIONS AND MARKETS IN UROLOGY
5.1 Urological Disease Incidence and Prevalence
5.2 Tissue Engineering and Regenerative Medicine Technologies for Urological Applications and Market Potential
5.2.1 Treatment of Urinary Incontinence and Bladder Repair
5.2.2 Ureter Repair and Replacement
5.2.3 Urethral Repair
5.2.4 Penile Reconstruction
5.2.5 Tissue Engineering for Treatment of Vesicoureteral Reflux
5.2.6 Gene Therapy for Urological Dysfunction
5.3 Market Forecast for Urological Applications
5.4 Market Drivers and Limiters
5.5 Leading Companies in Urological Tissue Engineering
CHAPTER 6: ORGAN REGENERATION TECHNOLOGIES AND MARKETS
6.1 Existing Products for Organ Supplementation
6.2 Organ Transplantation
6.3 Technologies for Organ Regeneration
6.3.1 Liver Regeneration
6.3.2 Pancreas and Islet Cell Regeneration
6.3.3 Kidney and Renal Tubule Regeneration
6.3.4 Small Intestine Regeneration
6.3.5 Bone Marrow Regeneration
6.3.6 Heart Regeneration
6.4 Emerging Markets for Organ Regeneration
6.5 Organ Regeneration Market Drivers and Limiters
6.6 Leading Companies in Organ Regeneration
CHAPTER 7: TISSUE ENGINEERING AND REGENERATIVE MEDICINE FOR WOUND MANAGEMENT, SKIN REPAIR AND SKIN ULCER TREATMENT
7.1 Wound and Skin Disease Incidence and Prevalence
7.2 Tissue Engineering and Cell Transplantation Technologies for Wound Management, Skin Repair and Skin Ulcer Treatment and Market Potential
7.2.1 Wound Management
7.2.2 Burn Treatment
7.2.3 Skin Ulcer Treatment
7.2.4 Hernia and Soft Tissue Repair
7.3 Market Analysis Forecast for Tissue Engineering and Regenerative Medicine Products for Wound Management, Skin Repair and Skin Ulcer Treatment
7.4 Market Drivers and Limiters
7.5 Competitor Analysis for Tissue Engineering and Regenerative Medicine Market for Wound Management, Skin Repair and Ulcer Treatment
CHAPTER 8: COMPETITOR ASSESSMENT
8.1 Overview of Tissue Engineering and Regenerative Medicine Companies
8.2 Acquisitions, Mergers and Partnerships to Improve Competitive Position
8.3 Technology Portfolio Analysis for Leading Tissue Engineering and Regenerative Medicine Companies
CHAPTER 9: COMPANY PROFILES
9.1 Aastrom Biosciences
9.2 Advanced BioHealing
9.3 Advanced Cell Technology
9.4 Aldagen
9.5 Arteriocyte
9.6 Athersys
9.7 Biofisica
9.8 Bioheart
9.9 BioMimetic Therapeutics
9.10 Cardium Therapeutics
9.11 CeraPedics
9.12 Cook Biotech
9.13 CrossCart
9.14 CryoLife
9.15 Cytograft Tissue Engineering
9.16 Cytori Therapeutics
9.17 Gamida Cell Ltd.
9.18 GeneGrafts
9.19 GenVec
9.20 Genzyme
9.21 Geron
9.22 Integra LifeSciences
9.23 International Stem Cell
9.24 Isolagen
9.25 LifeCell/Kinetic Concepts
9.26 Mesoblast
9.27 MicroIslet
9.28 Neuralstem
9.29 Novocell
9.30 Organogenesis
9.31 Orthopeutics
9.32 Osiris Therapeutics
9.33 Pluristem Therapeutics
9.34 ReGen Biologics
9.35 ReNeuron
9.36 Scil Technology
9.37 StemCells Inc.
9.38 StemCor Systems
9.39 Tengion
9.40 Tepha
APPENDIX – COMPANY LISTING
252 pages
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